influenza vaccine formulations for the 2022-23 season
Egg-based influenza vaccine licensed in the U.S. will contain hemagglutinin (HA) derived from an A/Victoria/2570/2019 (H1N1) pdm09-like virus, an A/Darwin/9/2021 (H3N2)-like virus, a B/Austria/1359417/2021(Victoria lineage)-like virus, and a B/Phuket/3073/2013 (Yamagata lineage)-like virus.
Cell- or recombinant-based influenza vaccines will contain an A/Wisconsin/588/2019 (H1N1) pdm09-like virus, an A/Darwin/9/2021 (H3N2)-like virus, a B/Austria/1359417/2021 (Victoria lineage)-like virus, and a B/Phuket/3073/2013-like (Yamagata lineage) virus.
What ACIP Recommends
Routine annual influenza vaccination is recommended for all persons aged 6 months or older who do not have contraindications. A licensed and age-appropriate vaccine formulation should be used for each recipient.
For the 2022-2023 flu season, three flu vaccines are preferentially recommended for people 65 years and older:
Fluzone High-Dose Quadrivalent vaccine
Flublok Quadrivalent recombinant flu vaccine
Fluad Quadrivalent adjuvanted flu vaccine
The Morbidity and Mortality Weekly Report published on August 26, 2022 provides guidance from the Advisory Committee on Immunization Practices (ACIP) for using this year’s flu vaccine products. View all available products on this printable listing of influenza vaccine products available for the 2022-23 season. Access the 2022-23 State Supplied Childhood Flu Vaccines At-A-Glance chart for formulations available to Washington State Childhood Vaccine providers.
administration of Influenza vaccines with other vaccines, including covid vaccines
Dosing for Children Aged 6 Months to Years OlD
Influenza vaccine dosing algorithm for children 6 months through 8 years -Advisory Committee on Immunization Practices, United States, 2022-23 influenza season.
For children aged 8 years who require 2 doses of vaccine, both doses should be administered even if the child turns age 9 years between receipt of doses 1 and 2.
Thimerosal in Flu Vaccine
Thimerosal is used as a preservative in all multi-dose vial presentations of influenza vaccine. A 0.5 milliliter (mL) dose drawn from a multi-dose vial contains up to 25 micrograms thimerosal, depending on the manufacturer. Single-dose flu vaccine presentations-prefilled syringe, single-dose vial, and single-use nasal spray-are thimerosal-free.
In Washington State, according to RCW 70A.230.120, "a person who is known to be pregnant or who is under three years of age shall not be vaccinated with a mercury-containing vaccine or injected with a mercury-containing product that contains more than 0.5 micrograms of mercury per 0.5 milliliter dose."
Vaccine expires 28 days after the multi-dose vial is opened or accessed (needle-punctured)
Vaccine is usable through the expiration date on the multi-dose vial label whether or not it has been opened or accessed
Resources for Flu Vaccine Administration
- CDC Preventing Seasonal Flu with Vaccination
- CDC Flu and People 65 years & older
- CDC Flu & Children
- Screening Checklist for Contraindications to Inactivated Injectable Influenza Vaccination (PDF)
- Screening Checklist for Contraindications to Live Attenuated Intranasal Influenza Vaccination (PDF)
- Vaccine Information Statement (Flu Vaccine, Inactivated or Recombinant)
- Vaccine Information Statement (Live, Intranasal)
- Links to Package Inserts for U.S.-licensed Vaccines
- CDC Flu Vaccine and People with Egg Allergies
- Is it COVID-19 or is it the flu? (PDF)