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SUMMARY: See this health alert for
Augmented Case & Contact Investigations for COVID-19
Using augmented resources, the Health District will now resume direct involvement in COVID-19 contact notification-and-home-quarantine, no longer delegating such to cases to execute. When the initial surge of cases occurred in late February through early March, the Health District was forced by circumstance to triage contact notification efforts, delegating most cases to notify contacts on their own. Case isolation and contact notification-and-quarantine has become a central strategy for suppression of transmission necessary to support a safe, incremental return to activity.
COVID-19 Clinical Trials
Consider referring patients to University of Washington studies addressing (1) treatment of cases and (2) post-exposure chemoprophylaxis for contacts of COVID-19.
The University of Washington is recruiting subjects for multi-site investigations of chemotherapy and chemoprophylaxis of COVID-19.
The treatment study for confirmed cases is a phase IIb, double-blinded, placebo-controlled, randomized trial designed to compare the efficacy of low dose hydroxychloroquine plus azithromycin versus placebo to prevent hospitalization and death in symptomatic adult outpatients with COVID-19. Inclusion criteria are:
The post-exposure prophylaxis (PEP) study for contacts will randomly assign participants to take hydroxychloroquine or a placebo over two weeks, and nasal swab samples will be collected and tested daily to confirm new COVID-19 infections across the two groups.
Both studies will use telemedicine as an interface, reducing time, transportation, and health care visit demands on participants.
To refer a patient, simply direct them to the appropriate web-site for self-enrollment:
Multi-System Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19
Be aware of an uncommon, new syndrome of severe inflammation with Kawasaki disease-like features associated with COVID-19 that is being reported in children.
Resources & Additional Reading
Source: adapted from Washington State Department of Health, May 15, 2020.
Note: data is incomplete for the most recent 7-10 day period.