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Perinatal Hepatitis B
This program provides support, education, and reminders to providers to ensure that all infants born to HBsAG+ mothers follow the CDC protocol to prevent contracting hepatitis B during delivery.
Hepatitis B Testing for Pregnant Women
All pregnant women should be tested for hepatitis B with every pregnancy.
Screening Pregnant Women for Hepatitis B Virus (HBV) Infection: Ordering Prenatal Hepatitis B Surface Antigen (HBsAg) Tests from Major Commercial Laboratories (PDF).
Under state law, providers must report HBsAG+ women to the Snohomish Health District within three working days as a notifiable condition.
To Report
- Monday through Friday from 8 a.m. to 5 p.m.
- Phone 425-339-5235
- Fax 425-338-8706
- Non-urgent after hours, leave a message at 425-339-5235
Perinatal hepatitis B Prevention Program Guidelines (PDF) is available online to assist prenatal providers, pediatricians, parents, hospitals, and local health jurisdictions.
Infant Protocol
These infants should receive HBIG and dose Number 1 of hepatitis B vaccine within 12 hours of birth. They should receive dose Number 2 at 1 to 2 months, dose Number 3 at 6 months (not sooner than 24 weeks), and should have post-vaccine serology at 9 to 12 months (typically at the 12 month well child check). This is an updated CDC protocol as of October 9, 2015.
Postvaccine serology is an HBsAG and an anti-HBs. If the HBsAg is negative and the anti-HBs is positive, the child is immune due to vaccination. As of January 2018, it is recommended that infants who test negative for anti-HBs be revaccinated with a single dose of hepatitis B vaccine and receive postvaccine serology 1 to 2 months later. Infants whose anti-HBs remain negative following single dose revaccination should receive 2 additional doses of hepatitis B vaccine to complete the second series, followed by postvaccine serology 1 to 2 months after the final dose. If they still show no protection, then they are termed a "non-responder" and are susceptible to hepatitis B infection. Parents/guardians should be counseled about the child receiving HBIG if exposed to someone infected with hepatitis B.
Fewer than 5% of persons who receive 6 doses of properly administered hepatitis B vaccine fail to respond to the vaccine successfully.
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Perinatal Hepatitis B Prevention
Phone: 425-252-5439Fax: 425-339-5253
Did You Know?
Hepatitis B vaccination and one dose of HBIG within 24 hours after birth are 85 to 95% effective in preventing perinatal HBV transmission.